The key is making time away from work -- totally away from work -- to get your life back in balance. It will take some effort on your part -- and perhaps the part of a friend or spouse -- to make the shift from a sole focus on work, but for your mental and physical well-being, you really should make the effort.
Block out "personal time" to spend with family and (non-work) friends.
When on the road for business, call home regularly to stayed connected.
Learn how to delegate work -- and learn to say no to new assignments (or at least learn not to be the first to volunteer to take the assignment).
Take time off, perhaps starting with a long weekend and gradually moving up to longer vacations -- and leave work behind.
Consider an exercise routine -- after clearing it with your doctor -- to get your body back to a healthy shape. And better, have a friend or significant other as your exercise buddy to make it more fun (and to keep your mind off work while working-out).
Consider volunteering -- to help others and to meet new people.
Convince yourself it is okay to sometimes just sit and relax and do nothing.
Find a hobby or two.
Fight the urge that everything you do must be perfect -- to your standards.
Accept that we all need a decent number of hours of sleep.
If you find yourself not able to do any of these suggestions, consider getting professional help to deal with what is basically an addiction.